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. 2023 Dec 20;625(7993):195–203. doi: 10.1038/s41586-023-06870-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — a. Fully annotated 2D [¹H,¹⁵N] HSQC spectrum of ¹⁵N-labeled ARPP19. b. Chemical Shift Index (CSI) and c. Secondary-structure propensity (SSP) data for ARPP19 plotted vs. residue numbers. (SSP > 0, α helix; SSP < 0, β strand). Cα and Cβ chemical shifts were used to create the CSI and SSP plots (RefDB database⁶²). Preferred secondary structure indicated above SSP data. d. Fully annotated 2D [¹H,¹⁵N] HSQC spectrum of ¹⁵N-labeled FAM122A_ID. e. CSI and f. SSP data for FAM122A_ID plotted vs. residue numbers; same as c. g. Fully annotated 2D [¹H,¹⁵N] HSQC spectrum of ¹⁵N-labeled tpS62tpS104ARPP19. h. CSI; same as c. i. CSI comparison between ARPP19 (black) and tpS62tpS104ARPP19 (red).