Table 2.

Risk factors for PMV in patients with influenza-related ARDS

	Univariate			Multivariate
	Odds ratio	95% confidence interval	p value	Odds ratio	95% confidence interval	p value
Body mass index (kg/m2)	1.046	0.992 ~ 1.103	0.095
BMI > 25 (kg/m2)	2.583	1.423 ~ 4.688	0.002	2.087	1.006 ~ 4.329	0.048
Cardiac disease	0.401	0.144 ~ 1.114	0.08
Combined with bacterial pneumonia onset before D21	3.893	2.120 ~ 7.149	< 0.001	4.115	2.002 ~ 8.456	< 0.001
Bacteremia onset before D21	2.619	1.244 ~ 5.517	0.011	1.821	0.755 ~ 4.391	0.18
APACHE II score	1.038	1.003 ~ 1.075	0.036	1.014	0.97 ~ 1.060	0.55
ECMO	8.062	3.428 ~ 18.964	< 0.001	6.181	2.338 ~ 16.336	< 0.001
Prone	1.785	0.934 ~ 3.411	0.079
Neuromuscular blockade > 48 h	3.985	2.149 ~ 7.389	< 0.001	2.800	1.334 ~ 5.879	0.007
Need for vasopressor agents	2.597	1.464 ~ 4.606	< 0.001	1.528	0.753 ~ 3.099	0.24
Acute kidney injury requiring renal replacement therapy a	2.647	1.016 ~ 6.896	0.046	2.578	0.778 ~ 8.543	0.121

ARDS acute respiratory distress syndrome, ECMO extracorporeal membrane oxygenation, APACHE II Acute Physiology and Chronic Health Evaluation

^aExcluding those with end-stage renal disease receiving regular hemodialysis