TABLE 4.

Observed versus predicted kidney clearance for TFV and OS for each subject.

ID	Observed TFV CLr	Predicted TFV CLr	P/O ratio of TFV CLr	Observed OC CLr	Predicted OC CLr	P/O ratio of OC CLr
1	240	244	1.02	257	263	1.02
2	197	233	1.18	225	253	1.12
3	231	301	1.30	230	328	1.43
5	236	154	0.65	232	163	0.70
6	36	48	1.33	48	50	1.04
13	64	75	1.17	69	80	1.16
14	87	102	1.17	74	117	1.58
15	82	113	1.38	115	122	1.06
16	111	123	1.11	130	132	1.02
18	76	76	1.00	102	81	0.79
22	128	152	1.19	94	163	1.73
23	179	158	0.88	193	172	0.89
24	464	287	0.62	361	309	0.86
25	181	171	0.94	205	184	0.90
30	116	153	1.32	58	166	2.86
31	209	146	0.70	247	160	0.65
33	248	187	0.75	281	200	0.71
34	195	181	0.93	308	198	0.64
35	260	187	0.72	297	201	0.68
36	163	143	0.88	167	153	0.92
38	105	103	0.98	112	125	1.12
41	124	236	1.90	265	277	1.05
42	404	363	0.90	440	405	0.92
45	177	204	1.15	157	241	1.54
46	143	174	1.22	157	197	1.25
49	38	34	0.89	36	39	1.08
51	61	48	0.79	75	51	0.68

Abbreviations: CL_r, renal clearance; OC, oseltamivir; P/O ratio, prediction‐over‐observation ratio of renal drug clearance; TFV, tenofovir.