Tuccillo 2002.

Methods	Study design: cross‐over RCT Study time frame: not stated Duration of follow‐up: 3 months
Participants	Country: Italy Setting: single centre Diuresis < 200 mL during interdialysis period; clinically stable; permanent vascular access; no diabetes, liver cirrhosis or oedema Number: 12 Sex (M/F): 7/5 Mean age ± SD: 53 ± 4 years Exclusion criteria: not stated
Interventions	Treatment group HDF with polysulfone Fresenius F8 1.8 m2 dialysis membrane, PMMA Filter B3‐2, 2 m2 Duration: 1 session in the acute phase, 3 months in the chronic phase QB: 315 to 345 mL/min QD: 500 mL/min Control group HD with polysulfone Fresenius F8 1.8 m2 dialysis membrane, PMMA Filters B3‐2, m2 Duration: 1 session in the acute phase, 3 months in the chronic phase QB: 315 to 345 mL/min QD: 500 mL/min Co‐interventions: not stated
Outcomes	Kt/V
Notes	Exclusions post randomisation but pre‐intervention: not stated Stop or end point/s: not stated Additional data requested from authors: none requested Funding: not stated
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not stated
Allocation concealment (selection bias)	Unclear risk	Not stated
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not stated
Blinding of outcome assessment (detection bias) All outcomes	Low risk	No blinding but review authors judge that outcome measurement not likely influenced
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Short duration of study, < 10% attrition
Selective reporting (reporting bias)	High risk	Data for end of first phase of treatment not available
Other bias	High risk	Carry over effect present because of the cross‐over design; data not extractable for meta‐analysis; abstract only publication