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. 2022 Sep 8;2(9):605–616. doi: 10.1038/s43588-022-00299-w

Fig. 6. MoGP trajectory patterns for secondary endpoints of ALS disease progression.

Fig. 6

Measures include a, forced vital capacity and b, ALSFRS-R subscores (fine motor, gross motor, bulbar, respiratory domains). Trajectory colors for each panel are unrelated and correspond to the relative number of participants in each cluster, scaled from the largest to the smallest of the five largest clusters from PRO-ACT. Participants with minimal change in score (≤1 point) were excluded from the model. n indicates the number of ALS patients in each cluster.