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. 2024 Jan 4;14(1):1. doi: 10.1038/s41408-023-00969-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A The schematic of the experiment. B–D The number of peripheral blood (PB) between IFN-α treatment and untreated mice in JAK2V617F/Vav-Cre donor mice and CD5.1 donor mice. B The number of white blood cells (WBC). C The number of platelets (PLT). D The percentage of hematocrit (HCT). Graph represents at least two independent experiments of each time point, each with 4 to 5 mice per group. E–G The percentage of CD45.2 (JAK2V617F/Vav-Cre cells) in blood chimerism of treated and untreated mice. Graph represents at least two independent experiments of each time point, each with 4 to 5 mice per group. E before treatment, F after 1 month of IFN treatment, and G after 2 months of IFN treatment. H The survival of treated and untreated mice. Data are mean ± SD *p < 0.05, **p < 0.01, ***p < 0.001.