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. 2024 Jan 4;15:275. doi: 10.1038/s41467-023-44237-4

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© The Author(s) 2024, corrected publication 2024

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Fig. 3 — a Compound structures of the DCAF1-BRD9 PROTAC DBr-1, the VHL-BRD9 PROTAC VZ185 and the CRBN-BRD9 PROTAC dBRD9. b Immunoblot analysis of HEK293 BRD9-HiBiT/FF/CAS9 cells treated for 2 h with DBr-1, VZ185, and dBRD9 at various doses. c BRD9-HiBiT and BRD7-HiBiT signal detection of samples treated for 2 h with DBr-1, VZ185, and dBRD9 at various doses, DC50 values and maximal observed degradation are shown below. Data represents mean ± standard deviation from n = 3 replicates. Source data are provided as a Source Data file.