Fig. 2.

Representative structures of the inflammasome sensor proteins and the inflammasomes. a Representative structure of the inflammasome sensor proteins, including NLRPs (NLRP1 and NLRP3), NLRCs (NLRC4), and ALRs (AIM2). b Representative structure of the inflammasomes, including the NLRP1 inflammasome, the NLRP3 inflammasome, the NLRC4 inflammasome, and the AIM2 inflammasome. NLRs, nucleotide-binding domain, leucine-rich repeat-containing proteins; NLRPs, NLRs containing an N-terminal pyrin domain (PYD); NLRCs, NLRs containing a caspase activation and recruitment domain (CARD); ALRs, absent in melanoma 2 (AIM2)-like receptor; NAIP, NLR apoptosis inhibitory protein. The figure was created by FIGDRAW