Table 2.
League table of HbA1c (upper right quarter) and proportion of the patients achieving HbA1c < 7% (lower left quarter).
| Placebo | −0.49 (−0.73, −0.26) | −0.66 (−0.86, −0.48) | −0.78 (−0.86, −0.70) | −0.84 (−1.03, −0.65) | −0.69 (−0.98, −0.40) | −0.74 (−1.38, −0.05) | −0.66 (−1.20, −0.12) | −0.27 (−0.53, −0.02) |
| 0.30 (0.07, 0.83) |
Teneligliptin
5 mg |
−0.17 (−0.42, 0.08) | −0.28 (−0.51, −0.05) | −0.35 (−0.60, −0.10) | −0.20 (−0.56, 0.17) | −0.24 (−0.93, 0.48) | −0.17 (−0.75, 0.45) | 0.22 (−0.11, 0.55) |
| 0.22 (0.08, 0.49) | 0.99 (0.21, 2.92) |
Teneligliptin
10 mg |
−0.11 (−0.30, 0.08) | −0.18 (−0.39, 0.04) | −0.03 (−0.36, 0.32) | −0.07 (−0.76, 0.63) | 0.00 (−0.57, 0.60) | 0.39 (0.09, 0.70) |
| 0.16 (0.09, 0.24) | 0.74 (0.18, 2.07) | 0.87 (0.30, 1.93) |
Teneligliptin
20 mg |
−0.06 (−0.25, 0.12) | 0.08 (−0.19, 0.36) | 0.04 (−0.60, 0.72) | 0.12 (−0.42, 0.65) | 0.50 (0.26, 0.74) |
| 0.11 (0.04, 0.24) | 0.48 (0.10, 1.39) | 0.56 (0.17, 1.35) | 0.70 (0.24, 1.58) |
Teneligliptin
40 mg |
0.15 (−0.19, 0.49) | 0.10 (−0.57, 0.81) | 0.18 (−0.39, 0.76) | 0.56 (0.26, 0.88) |
| 0.13 (0.03, 0.33) | 0.61 (0.08, 2.15) | 0.71 (0.13, 2.20) | 0.81 (0.24, 2.01) | 1.47 (0.27, 4.68) |
Sitagliptin
100 mg |
−0.04 (−0.78, 0.68) | 0.03 (−0.58, 0.63) | 0.42 (0.05, 0.78) |
| NA | NA | NA | NA | NA | NA |
Vildagliptin
100 mg |
0.08 (−0.80, 1.00) | 0.46 (−0.26, 1.14) |
| NA | NA | NA | NA | NA | NA | NA |
Metformin
500 mg |
0.38 (−0.20, 0.98) |
| NA | NA | NA | NA | NA | NA | NA | NA |
Bromocriptine
0.8 mg |
The relative effect sizes are measured as a mean difference (upper right quarter) or an odds ratio (lower left quarter) along with 95% CIs. The differences between the compared groups are deemed as significant when the 95% CIs did not contain 0.00 (upper right quarter) or 1.00 (lower left quarter). The results with significant differences are marked with blue background, and the results without significant differences are marked with gray background. The doses of all the antidiabetic drugs are daily dose. The unit of HbA1c is %. HbA1c, glycated hemoglobin A1c; NA, not available.