TABLE 2.

The results of the univariate and multivariate Cox regression analysis for OS.

	Univariate analysis			Multivariate analysis
	HR	95% CI	p	HR	95% CI	p
pT
1	reference			reference
2	1.103	0.581–2.092	0.763	0.836	0.348–2.008	0.689
3	4.027	0.890–18.219	0.070	1.228	0.062–24.257	0.892
4	6.398	1.406–29.106	0.016	0.795	0.092–6.836	0.835
pN
0	reference			reference
1	0.918	0.445–1.894	0.817	1.336	0.463–3.854	0.591
2	3.607	1.512–8.603	0.004	1.592	0.348–7.268	0.548
3	7.211	0.919–12.583	0.060	9.289	0.840–102.707	0.069
Grade
2	reference			reference
3	1.308	0.315–5.429	0.700	0.317	0.010–10.001	0.514
ALDH1
Negative	reference			reference
Focal	1.591	0.813–3.114	0.175	2.602	0.773–8.754	0.122
Diffuse	2.187	0.621–7.708	0.223	1.845	0.254–13.381	0.544
AnnexinA1
Negative	reference			reference
Focal	1.943	0.584–6.463	0.278	1.914	0.433–8.459	0.391
Diffuse	1.693	0.481–5.952	0.411	2.080	0.452–9.566	0.346
CD44
Negative	reference			reference
Focal	0.636	0.277–1.459	0.285	0.669	0.210–2.134	0.497
Diffuse	0.428	0.206–0.888	0.022	0.460	0.154–1.373	0.164
CD117*
Negative	reference			reference
Focal	0.577	0.246–1.350	0.205	0.225	0.028–1.776	0.157
Diffuse	0.764	0.377–1.551	0.457	2.025	0.186–21.978	0.561
CD117**
Negative	reference			reference
Focal	0.377	0.165–1.345	0.078	0.615	0.082–4.589	0.635
Diffuse	0.441	0.212–1.331	0.104	0.076	0.006–0.929	0.043
CD166
Negative	reference			reference
Focal	3.699	0.794–17.226	0.095	9.020	0.313–259.600	0.199
Diffuse	3.131	0.740–13.244	0.120	11.974	0.472–303.720	0.132
Nanog
Negative	reference			reference
Focal	0.907	0.384–2.140	0.823	0.404	0.112–1.447	0.164
Diffuse	1.414	0.647–3.092	0.384	1.491	0.542–4.099	0.438
oct-4
Negative	reference			reference
Focal	0.866	0.425–1.764	0.692	0.873	0.309–2.464	0.798
Diffuse	1.672	0.652–4.287	0.283	2.904	0.680–12.388	0.149

Membranous (*); membranous and/or cytoplasmic (**) immunostaining.

Significant variables are highlighted in bold.