TABLE 3.

The results of the univariate and multivariate Cox regression analysis for DFS.

	Univariate analysis			Multivariate analysis
	HR	95%CI	p	HR	95%CI	p
pT
1	reference			reference
2	1.029	0.595–1.781	0.915	0.839	0.411–1.711	0.629
3	6.008	1.749–20.635	0.004	16.835	1.539–184.083	0.020
4	5.497	1.881–16.058	0.001	2.200	0.402–12.027	0.362
pN
0	reference			reference
1	1.249	0.702–2.220	0.448	1.007	0.448–2.262	0.986
2	2.708	1.224–5.991	0.013	1.045	0.265–4.111	0.949
3	19.754	4.031–96.790	<0.001	11.365	1.290–100.067	0.028
Grade
2	reference			reference
3	1.037	0.324–3.318	0.950	4.273	0.359–50.843	0.250
ALDH1
Negative	reference			reference
Focal	1.889	1.052–3.077	0.044	2.539	1.032–6.245	0.042
Diffuse	1.775	0.602–5.230	0.297	2.858	0.633–12.894	0.171
AnnexinA1
Negative	reference			reference
Focal	0.931	0.425–2.037	0.858	0.665	0.245–1.804	0.424
Diffuse	1.063	0.467–2.420	0.884	0.828	0.282–2.427	0.731
CD44
Negative	reference			reference
Focal	0.637	0.306–1.326	0.227	0.626	0.233–1.676	0.351
Diffuse	0.625	0.337–1.162	0.137	0.582	0.237–1.431	0.238
CD117*
Negative	reference			reference
Focal	0.668	0.315–1.415	0.292	0.859	0.136–5.408	0.872
Diffuse	1.136	0.624–2.066	0.675	0.730	0.129–4.118	0.722
CD117**
Negative	reference			reference
Focal	0.453	0.212–1.101	0.061	0.472	0.081–2.737	0.403
Diffuse	0.758	0.400–1.438	0.397	0.524	0.080–3.425	0.500
CD166
negative	reference			reference
Focal	1.670	0.594–4.696	0.330	1.390	0.329–5.863	0.653
Diffuse	1.221	0.479–3.111	0.674	0.743	0.201–2.746	0.656
Nanog
Negative	reference			reference
Focal	0.959	0.481–1.910	0.906	0.701	0.268–1.829	0.468
Diffuse	1.092	0.548–2.174	0.801	1.650	0.714–3.811	0.240
oct-4
Negative	reference			reference
Focal	0.624	0.347–1.123	0.115	0.802	0.358–1.798	0.592
Diffuse	0.911	0.397–2.091	0.827	0.684	0.208–2.254	0.533

Membranous (*); membranous and/or cytoplasmic (**) immunostaining.

Significant variables are highlighted in bold.