TABLE 4.
The results of the multivariate Cox regression analysis for OS and DFS, including the markers which showed statistical impact on survival in the univariate Cox regression analysis.
| OS | DFS | |||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | |
| pT | ||||||
| 1 | reference | reference | ||||
| 2 | 0.894 | 0.460–1.737 | 0.741 | 0.877 | 0.500–1.538 | 0.647 |
| 3 | 1.369 | 0.150–12.426 | 0.779 | 2.768 | 0.454–16.868 | 0.269 |
| 4 | 1.155 | 0.190–7.006 | 0.875 | 2.167 | 0.505–9.298 | 0.297 |
| pN | ||||||
| 0 | reference | reference | ||||
| 1 | 0.953 | 0.4462.036 | 0.901 | 1.140 | 0.634–2.053 | 0.659 |
| 2 | 3.367 | 1.210–9.371 | 0.020 | 1.895 | 0.614–5.848 | 0.266 |
| 3 | 10.179 | 1.143–90.640 | 0.037 | 12.041 | 2.036–71.210 | 0.006 |
| ALDH1 | ||||||
| Negative | reference | |||||
| Focal | 1.832 | 1.014–3.410 | 0.048 | |||
| Diffuse | 2.029 | 0.655–6.288 | 0.219 | |||
| CD44 | ||||||
| Negative | reference | |||||
| Focal | 0.665 | 0.279–1.582 | 0.356 | |||
| Diffuse | 0.386 | 0.172–0.862 | 0.020 | |||
Significant variables are highlighted in bold.