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. 2024 Jan 4;15(1):3. doi: 10.1038/s41419-023-06389-5

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — The circRNAs involving in MAPK signaling pathway to regulate cell proliferation under the settings of various tumors, such as circ-MAPK4/miR-125a-3p/p38/MAPK, circ_PTN/miR-122/SOX6/MAPK/ERK, and circ-TLK1/miR-17-5p/PANX1/MAPK/ERK axis in glioma; circDHPR/miR-3194-5p/RASGEF1B/RAS/MAPK, circASAP1/miR-326 and miR-532-5p/MAPK1, circSETD3/miR-421/MAPK14 pathway in hepatocellular carcinoma; circDNAJC11/TAF15/MAPK6, circBACH2/hsa-miR-944/HNRNPC/MAPK, and circ_0006528/miR-7-5p/Raf1/MAPK/ERK pathway in breast cancer; circRNA C190/EGFR/MAPK/ERK, circ-ZKSCAN1/miR-330-5p/FAM83A/MAPK, and circ0001313/microRNA-452/HMGB3/ERK/MAPK axis in NSCLC; circMAPK1- encoded protein MAPK1-109aa/MEK1/MAPK1, hsa_circ_0044301/hsa-miR-188-5p/DAXX, and hsa-circ-0052001/hsa-miR-608/MAPK pathway in gastric cancer.