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. 2024 Jan 4;14:559. doi: 10.1038/s41598-024-51243-z

Figure 3.

Figure 3

miR-374a-5p targeted WNT signaling (A) qRT-PCR detection of WNT5A, WNT3, and WNT2B expression. (B) WB detection of WNT5A, WNT3, and WNT2B expression. *P < 0.05 vs. Sham. (C) Pearson correlation analysis of the expression of miR-374a-5p and WNT5A, WNT3, and WNT2B. (D) WB detection of WNT5A expression. *P < 0.05 vs. Sham, &P < 0.05 vs. IA + inhibitor NC. (E) Bioinformatics prediction of miR-374a-5p targeting of WNT signaling (WNT2B, WNT3, and WNT5A). (F) To validate the targeting relationship between miR-374a-5p and WNTA5, a dual luciferase reporter assay was conducted. *P < 0.05 vs. miR-374a-5p NC. n = 3.