Table 3.
Breakdown of mean TDIS total score by each PGIC score: End of double-blind KINECT3
| PGIC score | Number of patients | Total TDIS score, mean (SD) | Change from baseline to Week 6 in TDIS total score, mean (SD) |
|---|---|---|---|
| 1 | 22 | 3.5 (4.31) | − 7.68 (8.60) |
| 2 | 44 | 11.09 (8.31) | − 5.77 (7.04) |
| 3 | 83 | 12.36 (8.63) | − 3.90 (6.19) |
| 4 | 46 | 12.13 (8.53) | − 1.50 (5.78) |
| 5 | 6 | 15.0 (6.57) | 0.67 (6.77) |
| Total | 201 | 11.14 (8.52) | − 4.04 (6.86) |
PGIC Patient Global Impression of Change, SD Standard deviation, TDIS Tardive Dyskinesia Impact Scale
PGIC rated on the following scale: 1 = very much improved, 2 = much improved, 3 = minimally improved, 4 = not changed, 5 = minimally worse, 6 = much worse, 7 = very much worse
No patient reported a score of 6 (much worse) or 7 (very much worse)