Figure 3. Effect of tDCS on the nociceptive threshold response by the von Frey electronics test of rats in development. Control (C); Control + sham tDCS (C + sham-tDCS); Control + tDCS (C + tDCS); Sham Lesion (SL); Sham lesion + sham-tDCS (SL + sham tDCS); Sham lesion + tDCS (SL + tDCS); Neuropathic pain (NP); Neuropathic pain + sham-tDCS (NP + sham-tDCS); Neuropathic pain + tDCS (NP + tDCS). Data are presented as the mean ± SD, (n = 7–11). Different letter subscripts (a through j) indicate a statistically significant difference between the groups. Panel A: Threshold at baseline and 14 days after surgery C (n = 30), SL (n = 25), NP (n = 30). Panel B: Effects of tDCS 1 day and 7 days after the end of treatment (GEE/Bonferroni Interaction time x group (Wald χ2 = 1,709.97; 24, P < 0.001, n = 7–11; C (n = 10), C + sham-tDCS (n = 10), C + tDCS (n = 10), SL (n = 7), SL + sham-tDCS (n = 9), SL + tDCS (n = 9), NP (n = 9), NP + sham-tDCS (n = 10), NP + tDCS (n = 11)).
