Acevedo 2006.

Methods	Randomised, controlled, single‐centre, donor‐recipient study
Participants	60 oocyte donors 18 to 35 years of age with normal menstrual cycle: no PCOS, endometriosis, hydrosalpinges or severe male factor. 98 recipients 34–47 years of age received oocyte, but only 60 participants were analysed. Baseline characteristics: Most donors had similar basal ovarian conditions: basal FSH 5.2 vs 2.3 mIU/mL; E2 44.1 vs 32.5 pg/mL
Interventions	Ovarian stimulation: fixed dose of 150 IU rFSH on cd 3/4 f + 0.25 mg/d sc orgalutran + 75 IU/d of LH Intervention: 0.2 mg, SC triptorelin vs 250 μg/mL SC rHCG Luteal phase support (recipients): E2 plus 600 mg/d natural progesterone
Outcomes	Donors Primary outcome: OHSS Secondary outcomes: FSH and LH units (IU), GnRH antagonist ampoules, E2 levels, follicle numbers on day 5 of COH and on HCG day Recipients Pregnancy rates, implantation rates
Notes	98 recipients were included in the study, but for statistical techniques, only one participant of those who received oocytes from the same donor was included in the analysis Participants received embryos originating from donors; some donors gave oocytes to 2 recipients. Only 1 recipient was randomly included in the statistical analysis
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated list
Allocation concealment (selection bias)	High risk	Reported that allocation was not concealed (after contact was made with study author)
Blinding (performance bias and detection bias) FOR OHSS OUTCOME	High risk	Participants, those administering the interventions and those assessing the outcomes were not blinded to group assignment. Risk applies to assessment of OHSS
Incomplete outcome data (attrition bias) All outcomes	Low risk	No outcome data were missing
Selective reporting (reporting bias)	Unclear risk	Study protocol is not available. Live birth rates were not reported
Other bias	Low risk	No other potential bias was identified