Babayof 2006.

Methods	Randomised, controlled, single‐centre study
Participants	28 women with PCOS for IVF. Basic clinical characteristics: Both groups were similar in age: 30.1 vs 29.3, BMI 24.1 vs 27.1 and cause of infertility; 5.8 vs 5.3 and basal FSH (IU/L) 7.8 vs 4.3
Interventions	Ovarian stimulation: adjustable dose of 225 IU SC rFSH + 0.25 mg SC cetrotide Intervention: 0.2 mg decapeptyl vs 250 μg rHCG Number of embryos transferred: GnRH agonist group vs HCG group (mean: 2.3 ± 0.2 vs 2.2 ± 0.4) Luteal phase support: 50 mg/d of progesterone IM ± 4 mg/d E2 PO (if serum E2 concentration was below 200 pmol/L ± doubled dose of progesterone if serum progesterone concentration was below 40 nmol/L)
Outcomes	Primary outcome: serum levels of inhibin A, VEGF, TNFa, E2 and progesterone and incidence of OHSS Secondary outcomes: ovarian size and pelvic fluid accumulation, live birth, ongoing, chemical, miscarriage, number of oocytes retrieved, number of MII oocytes, fertilisation rate and number of embryos transferred
Notes	OHSS classification:Golan 1989 HCG group: 2 cases of ET were cancelled, and all embryos were frozen as the result of severe OHSS with accumulation of large amount of free fluid in the pelvis
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomisation list
Allocation concealment (selection bias)	Low risk	An independent nurse dispensed HCG or GnRH agonist according to a randomisation list
Blinding (performance bias and detection bias) FOR OHSS OUTCOME	High risk	Participants, those administering interventions and those assessing outcomes were not blinded to group assignment. Risk applies to assessment of OHSS
Incomplete outcome data (attrition bias) All outcomes	Low risk	No outcome data were missing
Selective reporting (reporting bias)	Low risk	Study protocol is not available, but it is clear that published reports include most expected outcomes
Other bias	Low risk	No other potential bias was identified