Primary mouse hepatocytes. |
|
|
Control (n=3) |
No treatment |
|
IL-17 protein (n=3) |
IL-17 protein |
|
NC (n=3) |
IL-17 protein |
|
STAT3-OE (n=3) |
IL-17 protein, STAT3-OE lentivirus |
|
si-NC (n=3) |
IL-17 Protein, scrambled shRNA lentivirus |
|
si-STAT3 (n=3) |
IL-17 protein, si-STAT3 lentivirus |
|
IL-17 nAbs (n=3) |
IL-17 nAb |
|
IL-17 nAbs+STAT3-OE (n=3) |
IL-17 nAb, STAT3-OE lentivirus |
Mice |
|
|
Control (n=6) |
No treatment |
|
Model (n=6) |
ConA |
|
IL-17 nAbs (n=6) |
IL-17 nAb, ConA |
|
NC (n=6) |
ConA |
|
si-NC (n=6) |
Scrambled shRNA lentivirus, ConA |
|
STAT3-OE (n=6) |
STAT3-OE lentivirus, ConA |
|
si-STAT3 (n=6) |
si-STAT3 lentivirus, ConA |
|
IL-17 nAbs+STAT3-OE+CoA (n=6) |
IL-17 nAb, STAT3-OE lentivirus, ConA |
|
STAT3-OE+CoA (n=6) |
STAT3-OE lentivirus, ConA |