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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: Am J Transplant. 2023 Sep 23;23(12):1980–1989. doi: 10.1016/j.ajt.2023.09.010

Table 2.

Post-transplant outcomes for older and younger ILDKT recipients.

Outcome Older vs younger ILDKT Interaction terma p for interactiona

Mortality 1.63 2.07 2.65 0.570.751.00 0.052b
DCGF 0.36 0.53 0.77 0.640.931.34 0.7
DGF 0.531.031.96 0.410.952.15 0.9
AR 0.39 0.54 0.74 0.510.781.19 0.2
LOS 0.880.981.10 0.820.951.10 0.5

Bold indicates p<0.05

a

Interaction term and p-value evaluating whether age modified the relationship between ILDKT and post-transplant outcomes

b

Sensitivity analysis excluding PLNF: interaction term=0.570.761.01, p=0.06

AR, Acute rejection; DCGF, death-censored graft failure; DGF, delayed graft function; LOS, length of stay.

Older ILDKT recipients have a 2.07-fold higher mortality risk compared to younger ILDKT recipients. When compared to younger CLDKT recipients, younger ILDKT have a 51% increased mortality risk (aHR: 1.311.511.75, p<0.001). Among older recipients, this risk is attenuated and not statistically significant (aHR: 0.891.141.45, p=0.3); the interaction between age and incompatibility status was not statistically significant (p interaction=0.052).