Table 2.
Outcome | Older vs younger ILDKT | Interaction terma | p for interactiona |
---|---|---|---|
| |||
Mortality | 1.63 2.07 2.65 | 0.570.751.00 | 0.052b |
DCGF | 0.36 0.53 0.77 | 0.640.931.34 | 0.7 |
DGF | 0.531.031.96 | 0.410.952.15 | 0.9 |
AR | 0.39 0.54 0.74 | 0.510.781.19 | 0.2 |
LOS | 0.880.981.10 | 0.820.951.10 | 0.5 |
Bold indicates p<0.05
Interaction term and p-value evaluating whether age modified the relationship between ILDKT and post-transplant outcomes
Sensitivity analysis excluding PLNF: interaction term=0.570.761.01, p=0.06
AR, Acute rejection; DCGF, death-censored graft failure; DGF, delayed graft function; LOS, length of stay.
Older ILDKT recipients have a 2.07-fold higher mortality risk compared to younger ILDKT recipients. When compared to younger CLDKT recipients, younger ILDKT have a 51% increased mortality risk (aHR: 1.311.511.75, p<0.001). Among older recipients, this risk is attenuated and not statistically significant (aHR: 0.891.141.45, p=0.3); the interaction between age and incompatibility status was not statistically significant (p interaction=0.052).