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. 2023 Nov 13;52(D1):D183–D193. doi: 10.1093/nar/gkad1016

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Results of ‘Pathway Downstream Analysis’ function. (A) Model diagram of pathway analysis. (B) User input 2833 differentially expressed genes associated with pulmonary hypertension. (C) Results overview for ‘Pathway Downstream Analysis’ function. (D) When clicking on the ‘detail’ button, target genes of the terminal TFs could be found. (E) Details of the TF and their target genes in the corresponding T(co)F knockdown/knockout datasets could be viewed by clicking on ‘Dataset ID’. (F) Detailed information on the target gene overview and the abundant (epi)genetic annotations could be viewed by clicking on ‘Target Gene’.