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. 2023 Nov 22;52(D1):D579–D585. doi: 10.1093/nar/gkad1086

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — ABC-HuMi search, browse, and visualization functionality. The BLAST search (A) identifies biosynthetic gene clusters (BGCs) harboring homologs of the user-provided sequence. The search result page (B, top) enables browsing of the BGC metadata (B, bottom) and the corresponding embedded antiSMASH reports (C). The metadata table links to the gene cluster family (GCF) or clan (GCC) of a BGC, thus allowing one to browse all similar clusters (D). GCC and GCF networks can also be visualized via interactive Cytoscape plots (E). Here, all nodes of a GCF are titled with the BGC identifiers and colored according to the corresponding human body site: the selected blue node is from the gut, green and pink nodes are from the oral microbiome and red ones are from the respiratory system.