Table 1.
RNA modification statistics across 62 species in RMBase v3.0
| Species | m6A | m1A | m5C | Ψ | 2′-O-Me | m7G | A-I | ac4C | Others |
|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | 234464 | 1162 | 46025 | 15078 | 8490 | 919 | 144122 | 1861 | 1484 |
| Mus musculus | 220022 | 91 | 47839 | 22518 | 1193 | 55 | 8864 | 0 | 950 |
| Macaca mulatta | 16699 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Pan troglodytes | 27828 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Rattus norvegicus | 43880 | 75 | 118 | 1317 | 3418 | 46 | 10 | 24 | 977 |
| Sus scrofa | 62116 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Mesocricetus auratus | 0 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 9 |
| Oryctolagus cuniculus | 0 | 88 | 98 | 225 | 46 | 70 | 0 | 0 | 493 |
| Ovis aries | 0 | 24 | 35 | 35 | 0 | 15 | 0 | 0 | 132 |
| Bos taurus | 0 | 127 | 94 | 381 | 105 | 29 | 0 | 16 | 770 |
| Arabidopsis thaliana | 35373 | 0 | 0 | 76 | 286 | 0 | 0 | 0 | 0 |
| Brassica napus | 0 | 49 | 0 | 175 | 128 | 59 | 0 | 0 | 425 |
| Chlamydomonas reinhardtii | 0 | 0 | 2 | 30 | 34 | 0 | 0 | 0 | 9 |
| Cucumis sativus | 0 | 12 | 14 | 34 | 0 | 0 | 0 | 0 | 105 |
| Glycine max | 0 | 0 | 0 | 4 | 1 | 1 | 0 | 0 | 7 |
| Nicotiana tabacum | 0 | 25 | 0 | 134 | 123 | 0 | 0 | 0 | 296 |
| Phaseolus vulgaris | 0 | 35 | 19 | 78 | 42 | 15 | 0 | 12 | 256 |
| Solanum tuberosum | 0 | 18 | 14 | 46 | 17 | 0 | 0 | 16 | 117 |
| Spinacia oleracea | 0 | 11 | 0 | 89 | 81 | 17 | 0 | 0 | 251 |
| Zea mays | 0 | 0 | 0 | 15 | 9 | 0 | 0 | 0 | 33 |
| Bombyx mori | 0 | 82 | 178 | 185 | 95 | 33 | 0 | 0 | 453 |
| Caenorhabditis elegans | 0 | 0 | 0 | 296 | 151 | 0 | 18 | 0 | 106 |
| Xenopus laevis | 0 | 55 | 86 | 104 | 46 | 35 | 0 | 0 | 270 |
| Danio rerio | 5071 | 0 | 0 | 5 | 40 | 0 | 0 | 0 | 0 |
| Gallus gallus | 0 | 4 | 0 | 36 | 55 | 2 | 0 | 0 | 37 |
| Candida albicans | 0 | 1 | 1 | 3 | 1 | 0 | 0 | 1 | 6 |
| Fusarium graminearum | 0 | 0 | 0 | 0 | 0 | 0 | 48493 | 0 | 0 |
| Fusarium verticillioides | 0 | 0 | 0 | 0 | 0 | 0 | 5227 | 0 | 0 |
| Neurospora crassa | 0 | 22 | 14 | 36 | 0 | 10 | 47345 | 0 | 134 |
| Pichia jadinii | 0 | 40 | 43 | 108 | 31 | 17 | 0 | 7 | 311 |
| Saccharomyces cerevisiae | 24486 | 151 | 231 | 2147 | 263 | 75 | 66 | 120 | 1767 |
| Schizosaccharomyces pombe | 1 | 8 | 8 | 41 | 18 | 9 | 0 | 0 | 87 |
| Drosophila melanogaster | 56 | 78 | 46 | 614 | 559 | 47 | 5049 | 13 | 494 |
| Tetrahymena thermophila | 0 | 50 | 49 | 165 | 81 | 0 | 0 | 0 | 205 |
| Bacillus subtilis | 15 | 6 | 0 | 99 | 3 | 39 | 0 | 0 | 185 |
| Clostridium acetobutylicum | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
| Escherichia coli | 243 | 0 | 21 | 206 | 55 | 66 | 4 | 2 | 508 |
| Geobacillus stearothermophilus | 1 | 3 | 0 | 11 | 5 | 3 | 0 | 0 | 25 |
| Halobacterium salinarum | 0 | 0 | 10 | 17 | 10 | 0 | 0 | 0 | 31 |
| Halococcus morrhuae | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| Haloferax volcanii | 0 | 0 | 51 | 79 | 51 | 0 | 0 | 5 | 167 |
| Lactococcus lactis | 11 | 2 | 0 | 0 | 0 | 30 | 0 | 1 | 64 |
| Mycobacterium smegmatis | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
| Mycoplasma capricolum | 12 | 10 | 0 | 38 | 2 | 17 | 0 | 0 | 78 |
| Mycoplasma mycoides | 4 | 1 | 0 | 4 | 0 | 3 | 0 | 0 | 14 |
| Pseudomonas aeruginosa | 1560 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Pyrococcus abyssi | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Rhodospirillum rubrum | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 4 |
| Salmonella typhimurium | 0 | 0 | 0 | 19 | 7 | 3 | 0 | 0 | 42 |
| Spiroplasma citri | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 3 |
| Streptomyces coelicolor A3 (2) | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| Streptomyces griseus | 0 | 26 | 0 | 4 | 25 | 18 | 0 | 0 | 48 |
| Sulfolobus acidocaldarius | 0 | 1 | 1 | 0 | 4 | 0 | 0 | 0 | 1 |
| Sulfolobus solfataricus | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 24 |
| Synechococcus elongatus PCC 6301 | 0 | 0 | 0 | 8 | 1 | 1 | 0 | 0 | 11 |
| Synechococcus sp.PCC 7002 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 0 | 5 |
| Synechocystis sp. | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3 |
| Thermoplasma acidophilum | 0 | 4 | 0 | 10 | 4 | 2 | 0 | 0 | 15 |
| Thermotoga maritima | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5 |
| Thermus thermophilus | 0 | 4 | 12 | 19 | 17 | 6 | 0 | 0 | 28 |
| Enterobacteria phage T4 | 0 | 0 | 0 | 14 | 6 | 3 | 0 | 0 | 39 |
| Enterobacteria phage T5 | 1 | 0 | 0 | 9 | 1 | 2 | 0 | 0 | 10 |
The table lists the number of sites for each RNA modification type in 62 species. m6A is N6-methyladenosine, m1A is N1-methyladenosine, m5C is 5-methylcytosine, Ψ is pseudouridylation, 2′-O-Me is 2′-O-methylation, m7G is N7-methylguanosine, A-I is a type of RNA editing, ac4C is N4-acetylcytidine, and ‘Others’ contains other RNA modification types.