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. 2024 Jan 5;25(1):3. doi: 10.1186/s10194-023-01707-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — TREM1 expression is highly upregulated in TNC microglia following repeated NTG administration. a, b Immunoblot analysis of TREM1 at the indicated times following NTG administration (n=6). c The white dashed box represents the TNC area. d Costaining of TREM1 with Iba1, NeuN, and GFAP within the TNC region. Scale bar: 20 μm. Values are the mean±SEM; one-way ANOVA and Tukey's post hoc tests; **p < 0.01 and ***p < 0.001 vs. the sham group