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. 2023 Nov 24;104(11):001920. doi: 10.1099/jgv.0.001920

Fig. 6.

Fig. 6.

Evolutionary patterns of coronavirus S protein sequence-containing DVGs under diverse selection pressures. (a) The deletions identified in DVGP50d-2 and DVGP90d-1 occurred under persistent infection at 50 and 90 days, respectively. (b) The mutation U was detected in DVGP50d-3 and DVGP10d-1 during persistent infection at 50 and 10 days, respectively. (c) The mutation U was identified in DVGP100dICGS-1 under triple pressures of persistent infection, innate immunity and antiviral treatment at 100 days. (d) The mutations A and U and the mutation U were identified in DVGP80d-1 and DVGP100dICGS-3 under persistent infection at 80 days and triple pressures of persistent infection, innate immunity and antiviral treatment at 100 days, respectively. (e) Mutations A and G in the nsp1 and nsp2 genes, respectively, were identified in DVGP100d-4. The mutation G was identified in both the S protein gene of the full-length genome P100d and DVGP100d-4.