Table 5:
Epidemiological, clinical and biochemical parameters of the cohort according to the incidence of CVEs.
| Variable | No CVE, n = 1999 | CVE, n = 188 | P-value |
|---|---|---|---|
| Age (years) | 61 (50; 68) | 64.5 (58; 70) | .000 |
| Sex (female), | 771 (38.6) | 54 (28.7) | .008 |
| Smoking | 1129 (56.5) | 124 (66) | .012 |
| Diabetes | 472 (23.6) | 83 (44.1) | .000 |
| Hypertension | 1814 (90.7) | 178 (94.7) | .07 |
| Dyslipemia | 1328 (66.4) | 139 (73.9) | .036 |
| CKD Stage | |||
| G3 | 802 (40.1) | 65 (34.6) | .185 |
| G4–5 | 662 (33.1) | 62 (33) | |
| G5D | 535 (26.8) | 61 (32.4) | |
| Body mass index (kg/m2) | 27.6 (24.68; 31.2) | 29 (25.8; 32.2) | .006 |
| Systolic blood pressure (mmHg) | 140 (128; 156) | 149 (132; 164) | .000 |
| Diastolic blood pressure (mmHg) | 81 (74; 89) | 81 (71; 89) | .705 |
| Pulse pressure (mmHg) | 59 (48; 71) | 68 (54; 80) | .000 |
| Total cholesterol (mg/dL) | 176 (152; 202) | 170.5 (141.2; 206) | .277 |
| HDL cholesterol (mg/dL) | 47 (39; 58) | 44 (34; 53) | .001 |
| LDL cholesterol (mg/dL) | 101 (79; 121) | 98 (72; 124) | .447 |
| Triglycerides (mg/dL) | 124 (91; 172) | 141 (103; 183) | .006 |
| Glucose (mg/dL) | 96 (87; 111) | 105 (91.2; 146.7) | .000 |
| Calcium (mg/dL) | 9.3 (9; 9.7) | 9.3 (8.9; 9.7) | .321 |
| Phosphate (mg/dL) | 3.8 (3.3; 4.5) | 4 (3.4; 5) | .017 |
| Sodium (mEq/L) | 140.1 (139; 142) | 140 (138; 142) | .016 |
| Potassium (mEq/L) | 4.8 (4.4; 5.2) | 4.9 (4.5; 5.3) | .002 |
| 25-OH vitamin D (ng/mL) | 15.19 (11.4; 19.5) | 13.15 (9.6; 17.2) | .000 |
| Plaque at baseline | 1377 (68.9) | 174 (92.6) | .000 |
| rs1800802 (CC) | 56 (82.4) | 12 (17.6) | .000 |
Qualitative variables are expressed as N (%). Quantitative variables are expressed as median (Q1; Q3).
Comparisons between groups was performed with Mann–Whitney U test for quantitative variables and Chi-squared test for categorical data.