Table 2:
COVID-19 outcomes and associations with CKD stage and dialysis modality in patients with CKD stage 3b–5 or dialysis.
| Number of events, % (N) | Incidence rate per 10 000 person-years (95% CI) | Univariate | Multivariate | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hospitalization or death before hospitalization | Death | Hospitalization or death before hospitalization | Death | Hospitalization or death before hospitalization | Death | Hospitalization or death before hospitalization | Death | |||||
| Characteristic | OR (95% CI) | P-value | OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | ||||
| CKD stagea | ||||||||||||
| 3b | 4.7 (102) | 1.2 (26) | 0.66 (0.55–0.81) | 0.17 (0.12–0.25) | Ref. | Ref. | Ref. | Ref. | ||||
| 4 | 6.1 (257) | 2.2 (91) | 0.88 (0.78–0.99) | 0.31 (0.25–0.38) | 1.33 (1.05–1.68) | .02 | 1.82 (1.17–2.83) | <.001 | 1.33 (1.05–1.68) | .02 | 1.66 (1.07–2.57) | .02 |
| 5 | 5.7 (82) | 2.0 (28) | 0.86 (0.69–1.06) | 0.29 (0.20–0.42) | 1.24 (0.92–1.67) | .16 | 1.65 (0.96–2.83) | .07 | 1.27 (0.94–1.71) | .12 | 1.59 (0.92–2.72) | .10 |
| Dialysis | 10.4 (419) | 3.6 (146) | 1.79 (1.62–1.97) | 0.62 (0.53–0.73) | 2.35 (1.88–2.93) | <.001 | 3.13 (2.05–4.77) | <.001 | 2.24 (1.79–2.81) | <.001 | 3.10 (2.03–4.74) | <.001 |
| Dialysis modalityb | ||||||||||||
| PD | 8.2 (71) | 3.7 (32) | 1.81 (1.63–2.02) | 0.59 (0.49–0.71) | Ref. | Ref. | Ref. | Ref | ||||
| HD | 11.0 (348) | 3.6 (114) | 1.34 (1.06–1.69) | 0.60 (0.43–0.85) | 1.39 (1.07–1.82) | .02 | 0.98 (0.66–1.46) | .92 | 1.30 (0.99–1.71) | .06 | 0.84 (0.56–1.28) | .42 |
Clinical outcomes are due to COVID-19. P is considered significant at P ≤ .05.
aMultivariate analysis adjusted for age, sex, primary kidney disease and CCI score.
bMultivariate analysis adjusted for age, sex, primary kidney disease, CCI score and dialysis vintage.