Figure 3.

Overview of PPIs found in HuRI, BioPlex, HIPPIE_F, and STRING_F databases. (A) Interactions are filtered according to the reference proteome. (B) Interactions with a PDB structure for both interacting proteins filtered to the reference proteome. (C) Interactions with a high-quality homology model for both interacting proteins filtered to the reference proteome. (D) Interactions with an AF model that have 85% of their residues predicted with ≥70% pLDDT score for both interacting proteins filtered to the reference proteome. HM: homology modeling, AF: AlphaFold.