Table 1.
Detailed information on mice used in each figure. In columns “Sections/Plates Analyzed”, “ROIs Analyzed”, “Age”, “Sex” and “Level of Spinal Column” information for each mouse is separated by commas. “ROIs Analyzed” corresponds to ROIs generated by automated analysis. In column “Level of Spinal Column” L1 refers to the first lumbar DRG and T12 refers to the twelfth thoracic DRG and if only L is shown the specific DRG is not known but the DRG is from the lumbar region.
| Figure | Genotype | Number of Mice (N) | Sections/plates Analyzed | ROIs Analyzed (n) | Age (Weeks) | Sex | Level of spinal column | Total ROIs analyzed |
|---|---|---|---|---|---|---|---|---|
| 1 | WT | 1 | 1 | 124 | 11 | M | L | 124 |
| 2 | WT | 5 | 3,4,10,8,4 | 52,172,476,437,134, | 16,7,7,7,7 | M,M,F,M,M | L,T12,T12,T12,T12 | 1271 |
| Kv2.1 KO | 5 | 4,7,5,4,5 | 232,124,576,293,239, | 16,7,7,7,7 | M,M,F,M,M | L,T12,T12,T12,T12 | 1124 | |
| 3 | WT | 8 | 4,11,4,6,4,4,4,6 | 238,126,1227,673,706,748,602,572, | 50,50,50,7,7,24,7,28 | M,M,M,M,M,M,M,F | L,T12,T12,T12,T12,T12,L1,T12 | 4892 |
| Kv2.2 KO | 8 | 3,6,7,4,4,4,4,5 | 359,209,853,400,913,719,729,745, | 50,50,50,7,7,24,7,28 | M,M,M,M,M,M,M,F | L,T12,T12,T12,T12,T12,L1,T12 | 4927 | |
| 4 | WT | 10 | 7,5,6,9,8 | 444,268,167,669,600, | 50,50,50,50,50 | F,F,F,M,M | T12,T12,T12,T12,T12 | 3419 |
| Kv2.1 KO | 7 | 5,6 | 298,324, | 50,50 | M,M | T12,T12 | 622 | |
| WT | 8 | same as data in figure 3 | ||||||
| Kv2.2 KO | 8 | same as data in figure 3 | ||||||
| 5 | WT | 3 | 4,16,17, | 104,379,328, | 18,19,19 | F,F,F | L,L,L | 811 |
| Kv2.1 Kv2.2 DKO | 2 | 5,14, | 108,274, | 18,19 | F,F | L,L | 382 | |
| 6 | WT DRG | 5 | 1,1,1,1,1 | 139,51,30,40,38 | 10,10,10,8,8 | M,M,F,F,M | T12,T8,L1,L1,L1 | 298 |
| WT Ventral Horn | 5 | 1,1,1,1,1 | 75,51,23,24,28 | 10,10,10,8,8 | M,M,F,F,M | T12,T8,L1,L1,L1 | 201 | |
| 7 | WT | 2 | 2 | N/A | 7,24 | M,M | L1,T12 | N/A |
| 8 | WT | 1 | 1 | N/A | 7 | M | L1 | N/A |
| Kv2.2 KO | 1 | 1 | N/A | 7 | M | L1 | N/A | |
| MrgprD-GFP | 1 | 1 | N/A | 13 | F | T12 | N/A | |
| 9 | WT | 1 | 1 | N/A | 28 | F | T12 | N/A |
| Kv2.2 KO | 1 | 1 | N/A | 28 | F | T12 | N/A | |
| 10 | WT | 1 | 1 | N/A | 10 | M | L5 | N/A |
| MrgprD-GFP | 4 | 6,5,9,14 | 852,632,842,1392, | 13,20,8,8 | F,M,F,F | T12,L1,L1,L1 | 3718 | |
| WT | 5 | 7,4,6,7,4 | 482,464,592,641,166, | 7,10,24,19,19 | F,M,M,F,F | L1,T12,T12,T12,T12 | 2345 | |
| PV-tdTomato | 2 | 15,9 | 1978,1158, | 8,8 | F,M | L1,L1 | 3136 | |
| 1–1 | WT | 1 | 1 | N/A | 10 | M | L5 | N/A |
| 1–2 | WT | 1 | 1 | N/A | 28 | M | L | N/A |
| 1–3 | WT | 1 | 3 | 125 | 13 | M | L | 125 |
| 2–1 | WT | 1 | 33 | 5399 | 8 | M | T11 and T12 | 5399 |
| 2–2 | MrgprDGFP | 1 | 1 | N/A | 13 | F | T12 | N/A |
| 2–3 | MrgprDGFP | 4 | 6,15,9,14 | 5,568,769,051,487 | 14,20,8,8 | F,M,F,F | L1,L1,L1,L1 | 3824 |
| WT | 2 | 7,5 | 771,478 | 24,8 | M,F | L1,L1 | 1249 | |
| 6–1 | WT DRG | 4 | 1,1,1,1 | 25,30,28,35 | 7,7,8 | M,F,F,F | L1,L1,L1,L1 | 118 |
| WT Ventral Horn | 4 | 1,1,1,1 | 17,19,26,19 | 7,7,8 | M,F,F,F | L1,L1,L1,L1 | 81 | |
| 7–1 | MrgprDGFP | 1 | 1 | N/A | 14 | F | T12 | N/A |
| WT | 2 | 1,1 | N/A | 11,17 | M,M | L,L | N/A | |
| 8–1 | WT | 1 | 1 | N/A | 7 | F | T12 | N/A |
| Kv2.1 KO | 1 | 1 | N/A | 7 | F | T12 | N/A |