Table 1. Clinical and epidemiological characteristics, and ventilatory and biochemical parameters at ICU admission of patients with severe COVID-19 who used the ELMO system, by treatment outcome.a .
| Characteristic | Total | Group | p | |
|---|---|---|---|---|
| Failure | Success | |||
| (n = 50) | (n = 22) | (n = 28) | ||
| Sex, male | 31 (62.0) | 11 (50.0) | 20 (71.4) | 0.121 |
| Age, years | 53.2 ± 13.6 | 53.8 ± 12.9 | 52.7 ± 14.3 | 0.940 |
| SAPS 3 | 57.21 ± 9.67 | 60.45 ± 9.44 | 53.80 ± 8.90 | 0.030 |
| Previous lung disease | 7 (14.0) | 4 (18.2) | 3 (10.7) | 0.684 |
| Diabetes mellitus | 10 (20.0) | 5 (22.7) | 5 (17.9) | 0.732 |
| Alcoholism | 3 (6.0) | 1 (4.5) | 2 (7.1) | 1.000 |
| Systemic arterial hypertension | 22 (44.0) | 11 (50.0) | 11 (39.3) | 0.449 |
| Hypoxemia (Spo2 < 92%) | 28 (56.0) | 15 (68.2) | 13 (46.4) | 0.124 |
| Dyspnea | 50 (100) | 22 (100) | 28 (100) | - |
| Ventilatory and biochemical parameters | ||||
| Spo2, mmHg | 89.47 ± 14.59 | 84.86 ± 21.21 | 92.93 ± 4.05 | 0.147 |
| pH | 7.44 ± 0.06 | 7.45 ± 0.04 | 7.43 ± 0.07 | 0.102 |
| Pao2, mmHg | 83.8 ± 30.8 | 81.6 ± 31.4 | 85.5 ± 30.8 | 0.538 |
| Paco2, mmHg | 37.1 ± 9.6 | 35.8 ± 7.2 | 38.2 ± 11.2 | 0.443 |
| HCO3, mmol/L | 24.7 ± 2.2 | 24.3 ± 2.2 | 25.0 ± 2.1 | 0.339 |
| BE, mmol/L | 1.2 [−0.2 to 2.3] | 0.2 [−1.1 to 2.5] | 1.25 [0.05-2.13] | 0.292 |
| Lactate, mmol/L | 1.73 [1.13-2.17] | 1.85 [1.13-2.52] | 1.48 [1.09-2.13] | 0.97 |
| Sao2, % | 93.2 ± 4.3 | 92.5 ± 4.9 | 93.7 ± 3.8 | 0.049 |
| Pao2/Fio2 | 126.3 ± 42.5 | 126.7 ± 49.1 | 125.9 ± 37.4 | 0.435 |
a
Values expressed as n (%), mean ± SD, or median [IQR]. SAPS 3: Simplified Acute Physiology Score 3; HCO3: bicarbonate; and BE: base excess.