Table 2. Multivariable Competing Risk Analysis for Cancer-Specific Death in Patients With Siewert Type II AEG.
| Variables | Before PSM, N (%) |
After PSM, N (%) |
||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age | ||||
| ≤ 56 | Ref | Ref | ||
| 56 - 75 | 1.176 (1.001 - 1.380) | 0.048 | 1.197 (0.976 - 1.469) | 0.084 |
| > 75 | 1.223 (0.951 - 1.572) | 0.12 | 1.106 (0.795 - 1.539) | 0.550 |
| Sex | ||||
| Male | Ref | Ref | ||
| Female | 0.934 (0.773 - 1.129) | 0.48 | 1.047 (0.839 - 1.307) | 0.680 |
| Race | ||||
| White | Ref | Ref | ||
| Black | 0.930 (0.682 - 1.268) | 0.65 | 0.789 (0.521 - 1.195) | 0.260 |
| Other | 0.759 (0.576 - 0.999) | 0.049 | 0.797 (0.567 - 1.122) | 0.190 |
| Grade | ||||
| G1 | Ref | Ref | ||
| G2 | 1.232 (0.848 - 1.790) | 0.27 | 1.588 (0.925 - 2.724) | 0.093 |
| G3 | 1.594 (1.103 - 2.303) | 0.013 | 2.227 (1.311 - 3.785) | 0.003 |
| G4 | 1.575 (0.887 - 2.798) | 0.12 | 1.714 (0.814 - 3.609) | 0.160 |
| T stage | ||||
| T1 | Ref | Ref | ||
| T2 | 1.745 (1.254 - 2.429) | < 0.001 | 1.642 (1.070 - 2.521) | 0.023 |
| T3 | 2.053 (1.496 - 2.819) | < 0.001 | 1.801 (1.199 - 2.705) | 0.004 |
| T4 | 2.808 (1.843 - 4.279) | < 0.001 | 2.276 (1.346 - 3.848) | 0.002 |
| N stage | ||||
| N0 | Ref | Ref | ||
| N1 | 1.594 (1.292 - 1.966) | < 0.001 | 1.500 (1.143 - 1.968) | 0.004 |
| N2 | 2.452 (1.948 - 3.086) | < 0.001 | 2.517 (1.872 - 3.386) | < 0.001 |
| N3 | 3.178 (2.453 - 4.117) | < 0.001 | 2.790 (2.014 - 3.864) | < 0.001 |
| RLN | ||||
| ≤ 10 | Ref | Ref | ||
| 10 - 16 | 0.774 (0.640 - 0.937) | 0.008 | 0.844 (0.659 - 1.080) | 0.180 |
| > 16 | 0.618 (0.519 - 0.735) | < 0.001 | 0.634 (0.505 - 0.797) | < 0.001 |
| Tumor size | ||||
| ≤ 19 | Ref | Ref | ||
| 19 - 44 | 1.159 (0.880 - 1.526) | 0.30 | 1.223 (0.844 - 1.770) | 0.290 |
| > 44 | 1.313 (0.983 - 1.752) | 0.065 | 1.700 (1.155 - 2.503) | 0.007 |
| Chemotherapy | ||||
| Yes | Ref | Ref | ||
| No | 1.143 (0.896 - 1.457) | 0.28 | 1.120 (0.826 - 1.518) | 0.470 |
| Radiotherapy | ||||
| Yes | Ref | Ref | ||
| No | 1.046 (0.875 - 1.251) | 0.62 | 1.198 (0.948 - 1.514) | 0.130 |
| Marital status | ||||
| Married | Ref | Ref | ||
| Unmarried | 1.160 (0.994 - 1.354) | 0.060 | 1.179 (0.975 - 1.426) | 0.089 |
AEG: adenocarcinoma of the esophagogatric junction; CI: confidence interval; HR: hazard ratio; RLN: number of removed lymph nodes; PSM: propensity score matching.