Table 3. Multivariable Competing Risk Analysis for Cardiovascular Death in Patients With Siewert Type II AEG.
| Variables | Before PSM, N (%) |
After PSM, N (%) |
||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age | ||||
| ≤ 56 | Ref | Ref | ||
| 56 - 75 | 2.149 (0.986 - 4.680) | 0.054 | 1.477 (0.594 - 3.670) | 0.400 |
| > 75 | 3.298 (1.294 - 8.410) | 0.012 | 3.389 (1.124 - 10.220) | 0.030 |
| Sex | ||||
| Male | Ref | Ref | ||
| Female | 0.884 (0.452 - 1.730) | 0.720 | 0.915 (0.408 - 2.050) | 0.830 |
| Race | ||||
| White | Ref | Ref | ||
| Black | 1.983 (0.899 - 4.370) | 0.090 | 3.274 (1.398 - 7.670) | 0.006 |
| Other | 1.430 (0.616 - 3.320) | 0.410 | 1.412 (0.428 - 4.660) | 0.570 |
| Grade | ||||
| G1 | Ref | Ref | ||
| G2 | 0.394 (0.139 - 1.110) | 0.079 | 0.702 (0.140 - 3.520) | 0.670 |
| G3 | 0.667 (0.244 - 1.820) | 0.430 | 0.764 (0.153 - 3.820) | 0.740 |
| G4 | 0.645 (0.072 - 5.760) | 0.700 | 1.652 (0.132 - 20.700) | 0.700 |
| T stage | ||||
| T1 | Ref | Ref | ||
| T2 | 0.817 (0.308 - 2.170) | 0.690 | 0.987 (0.246 - 3.960) | 0.990 |
| T3 | 0.772 (0.338 - 1.770) | 0.540 | 0.927 (0.286 - 3.000) | 0.900 |
| T4 | 0.628 (0.165 - 2.390) | 0.490 | 0.796 (0.151 - 4.200) | 0.790 |
| N stage | ||||
| N0 | Ref | Ref | ||
| N1 | 1.520 (0.684 - 3.380) | 0.300 | 1.288 (0.448 - 3.700) | 0.640 |
| N2 | 1.209 (0.461 - 3.170) | 0.700 | 2.095 (0.685 - 6.410) | 0.190 |
| N3 | 1.870 (0.773 - 4.530) | 0.170 | 2.310 (0.847 - 6.300) | 0.100 |
| RLN | ||||
| ≤ 10 | Ref | Ref | ||
| 10 - 16 | 0.751 (0.370 - 1.530) | 0.430 | 0.628 (0.245 - 1.610) | 0.330 |
| > 16 | 0.850 (0.446 - 1.620) | 0.620 | 0.705 (0.316 - 1.570) | 0.390 |
| Tumor size | ||||
| ≤ 19 | Ref | Ref | ||
| 19 - 44 | 2.227 (0.914 - 5.430) | 0.078 | 1.925 (0.556 - 6.670) | 0.300 |
| > 44 | 1.755 (0.677 - 4.550) | 0.250 | 1.207 (0.319 - 4.560) | 0.780 |
| Chemotherapy | ||||
| Yes | Ref | Ref | ||
| No | 1.857 (0.850 - 4.060) | 0.120 | 1.405 (0.423 - 4.670) | 0.580 |
| Radiotherapy | ||||
| Yes | Ref | Ref | ||
| No | 0.865 (0.411 - 1.820) | 0.700 | 0.591 (0.196 - 1.780) | 0.350 |
| Marital status | ||||
| Married | Ref | Ref | ||
| Unmarried | 1.860 (1.096 - 3.160) | 0.021 | 3.066 (1.372 - 6.850) | 0.006 |
AEG: adenocarcinoma of the esophagogatric junction; CI: confidence interval; HR: hazard ratio; PSM: propensity score matching; RLN: number of removed lymph nodes.