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. 2023 Dec 29;2023:1629777. doi: 10.1155/2023/1629777

Figure 2.

Figure 2

Ghrelin/GHSR axis attenuated intestinal epithelial tight junction injury in septic rats. (a) FITC-dextran serum levels were measured 4 hours after gastric administration to determine intestinal permeability. Higher serum FITC-dextran levels indicated more intestinal permeability. Serum LPS (b) and colon LPS (c) were assayed by ELISA. (d–g) Immunofluorescence (IF) analysis determining the expression and distribution of claudin-5 and ZO-1 in colon tissues of septic rats (100x magnification). ∗∗P < 0.01 (vs sham group), #P < 0.05 (vs CLP group), &P < 0.05 (vs ghrelin group), and &&P < 0.01 (vs ghrelin group).