Table 4.
Comparisons of pre-ICI ILA score between patients with and without ICI-related pneumonitis.
| All patients | Lung cancer patients | |||||
|---|---|---|---|---|---|---|
| ICI-related pneumonitis(+) | ICI-related pneumonitis(−) | p-valuea | ICI-related pneumonitis(+) | ICI-related pneumonitis(−) | P-valuea | |
| n = 23 | n =186 | n = 16 | n = 96 | |||
| Pre-ICI ILA Score | ||||||
| 0 | 11 | 103 | 8 | 41 | ||
| 1 | 10 | 53 | 7 | 35 | ||
| 2 | 1 | 21 | 0 | 12 | ||
| 3 | 1 | 9 | .428 | 1 | 8 | .570 |
| Features of lung abnormalities | ||||||
| Ground-glass attenuation | 10 | 79 | 1.000 | 7 | 53 | .429 |
| Reticular shadow | 9 | 59 | .486 | 5 | 40 | .584 |
| Honeycombing | 1 | 8 | 1.000 | 1 | 7 | 1.000 |
| Diffuse centrilobular nodularity | 0 | 3 | 1.000 | 0 | 0 | NA |
| Traction bronchiectasis | 3 | 26 | 1.000 | 1 | 19 | .296 |
| Radiation pneumonitis | 0 | 5 | 1.000 | 0 | 4 | 1.000 |
aFishier’s exact test.
Abbreviations: CT, computed tomography; ICI, immune checkpoint inhibitor; ILA, interstitial lung abnormality; NA, not available.