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. 2023 Aug 2;29(1):e97–e107. doi: 10.1093/oncolo/oyad220

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.

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Figure 3. — STEPP analysis of PFS and OS based on ETS in the GC and GS arms. (A) STEPP analysis of PFS at 12 weeks. (B) STEPP analysis of OS at 36 weeks. (C) STEPP analysis of the HR for PFS. (D) STEPP analysis of the HR for OS. The HRs for PFS and OS in the GS arm were comparable to those in the GC arm. Abbreviations: PFS: progression-free survival; OS: overall survival; ETS: early tumor shrinkage; STEPP: subpopulation treatment effect pattern plot; HR: hazard ratio; GC: gemcitabine plus cisplatin; GS: gemcitabine plus S-1.