Table 2.
Responses to the ACT-Q
| Mean score, interpretation (n) | |
|---|---|
| Barriers to participationc | |
| (2) The distance to the clinic is too far | 3.2, Slightly important (118) |
| (1) The time commitment required to participate | 2.9, Slightly important (118) |
| (6) I am concerned about the potential dangers and side effects of trial medicationsb | 2.9, Slightly important (119) |
| (7) I am worried about the possibility of being assigned to the placebo groupb | 2.7, Slightly important (117) |
| (3) I would not feel well enough to participate because of how my condition affects me | 2.6, Slightly important (119) |
| (5) I may not benefit personally from the development of new drugs | 2.4, Not at all (117) |
| (4) I am already participating in other research projects | 2.3, Not at all (116) |
| (8) I already feel I have a lot of appointments | 2.2, Not at all (118) |
| Reasons for participationc | |
| (12) I want to help other people with the same condition as me | 4.8, Very important (118) |
| (14) I want the opportunity to contribute to research | 4.6, Very important (119) |
| (9) I may get to try new medicines which are not available to everyone with my condition | 4.1, Quite important (119) |
| (10) I will get additional monitoring of how my condition is changing | 3.9, Quite important (119) |
| (11) I will receive more regular contact with medical staff | 3.7, Quite important (118) |
| (13) I have participated in research before and had a positive experienceb | 2.4, Slightly important (116) |
| Understanding of clinical trials and multi-arm multi-stage designa | |
| (15) Why clinical trials often need to have a group of people taking a placebo drug | 4.0, Good understanding (119) |
| (16) Why not everyone may be suitable to participate in a specific clinical trial | 4.0, Good understanding (118) |
| (17) Why researchers believe these experimental treatments may be effective | 3.9, Good understanding (119) |
| (19) Why having multiple ‘arms’ means we can test more than one drug and why this matters | 3.5, Some understanding, (119) |
| (18) What is a re-purposed medicine and why may it be effective in my condition | 3.4, Some understanding (119) |
c1 = Do not know, 2 = Not at all, 3 = Slightly important, 4 = Quite important, 5 = Very important
b1 = No understanding, 2 = Little understanding, 3 = Some understanding, 4 = Good understanding, 5 = Full understanding
aItems have been reverse scored, indicating less agreement with the attitude