Table 2.
Characteristics of ART-cycles in comparison of couples with/without SARS-CoV-2-infections (2022)
| All cycles (n = 335) | One or both partner with infections* (n = 124) | No infection1 (n = 211) | Mann–Whitney-U Chi-quadrat test (exact 2-sided) |
|
|---|---|---|---|---|
| Age (years) |
35.73 ± 3.99 (23.36–44.28) 36.16 (33.08; 38.79) |
35,96 ± 3.91 (23.36–42.87) 36.14 (34.04; 39.10) |
35.59 ± 4.05 (23.79–44.28) 36.29 (32.77; 38.68) |
p = 0.411 |
| Primary infertility | 178/335 (53.13%) | 61/124 (49.19%) | 117/211 (55.45%) | p = 0.308 |
| IVF treatment | 176/335 (52.54%) | 58/124 (46.77%) | 118/211 (55.92%) | p = 0.114 |
| Natural cycle IVF | 149/335 (44.48%) | 64/124 (51.61%) | 89/211 (42.18%) | p = 0.306 |
| Embryo transfer in cycles with oocytes | 239/306 (78.10%) | 87/114 (76.32%) | 152/192 (79.17%) | p = 0.570 |
| Blastocyst culture, if > 2 fertilized oocytes | 93/123 (75.61%) | 31/42 (73.81%) | 62/81 (76.54%) | p = 0.826 |
| Number of oocytes/retrieval |
5.50 ± 5.52 (0–24) 3 (1; 9) |
5.17 ± 5.41 (0–24), 2 (1; 9) |
5.69 ± 5.59 (0–23) 4 (1; 9) |
p = 0.454 |
| Number of fertilized oocytes |
2.84 ± 2.79 (0–13) 2 (1; 4) |
2.69 ± 2.83 (0–12), 1.5 (1; 4) |
2.92 ± 2.00 (0–13) 2 (1; 4) |
p = 0.293 |
| Fertilized oocytes/ retrieved oocytes |
52.87 ± 35.12 (0–100) 50 (2.90; 93) |
53.23 ± 36.17 50 (26.70; 100) |
52.66 ± 34.58 (0–100) 50 (28.93; 90) |
p = 0.925 |
| Number of embryos/transfer |
1.42 ± 0.52 (1–3) 1 (1; 2) |
1.37 ± 0.51 (1–3) 1 (1; 2) |
1.45 ± 0.53 (1–3) 1 (1; 2) |
p = 0.243 |
| Clinical pregnancy rate* | 78/239 (32.64%) | 19/87 (21.84%) | 59/152 (38.82%) | p = 0.010 |
| Miscarriage/pregnancy | 26/77 (33.77%) | 10/19 (52.63%) | 16/58 (27.59%) | p = 0.055 |
*Significant group differences < 0.05
1At least 1 partner with a proven SARS-CoV-2-infection within < 6 months prior to oocyte retrieval/pregnancy test