Table 1.
Descriptive statistics for HD participants (N = 57)
| Pre-manifest (n = 33) | Manifest (n = 24) | |||
|---|---|---|---|---|
| M (SD) | Range | M (SD) | Range | |
| Age* | 44.3 (10.8) | 29–65 | 54.7 (7.9) | 43–66 |
| Sex (n, Female) | 24 (72.7%) | – | 13 (54.2%) | – |
| Years of education | 14.4 (2.7) | 10–21 | 13.8 (3.4) | 10–26 |
| CAG | 41.6 (2.0) | 38–45 | 42.6 (2.0) | 37–46 |
| DBS* | 270.4 (87.3) | 101.5–450.0 | 383.7 (97.5) | 94.5–535.5 |
| TFC* | 12.7 (0.8) | 9–13 | 9.2 (2.1) | 6–13 |
| COGTEL* | 33.1 (10.3) | 10.6–51.4 | 19.1 (7.5) | 8.1–32.4 |
| NQ-Depression | ||||
| Raw score | 15.0 (6.6) | 8–33 | 16.6 (7.6) | 8–38 |
| T-score | 49.5 (6.2) | 36.9–64.6 | 50.5 (7.9) | 36.9–69.6 |
DBS Disease Burden Score, TFC Total Functional Capacity, COGTEL Cognitive Telephone Screening Instrument, NQ Neuro-QoL
CAG and DBS data are not reported for three participants (two pre-manifest, one manifest) whose genetic data was unavailable
*p < .05 for difference between pre-manifest and manifest groups