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. 2024 Jan 5;7:31. doi: 10.1038/s42003-023-05692-3

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© The Author(s) 2024, corrected publication 2024

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Fig. 8 — a Dynamic changes in transcriptomes of mat2aa and pole1 single and double mutants, as indicated by principal component analysis. b Venn diagram indicating the overlap of differentially expressed genes for down-regulated and up-regulated genes in fish of the indicated genotypes. c Expression patterns of genes in the four clusters of co-regulated genes identified in dnmt1 mutant fish; each column represents a biological replicate. d No restoration of expression levels in mat2aa/pole1 double mutants for the genes in the four groups identified in dnmt1 mutant fish; box plots (mean; box, upper/lower quartile; whiskers, minimal/maximal values).