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. 2023 Jan 28;309(1):183–193. doi: 10.1007/s00404-023-06916-x

Table 5.

Associations between dietary intakes and full blood count results during pregnancy with placental weight and birthweight

B P 95% CI
Lower Upper
Linear regression models for placental weight
 Trimester 1 dietary intakes
  Trimester 1 dietary iron (mg) vs. placental weight (g) 0.052 0.294 − 2.03 6.69
  Trimester 1 dietary folate (µg) vs. placental weight (g) 0.026 0.605 − 0.11 0.19
  Trimester 1 dietary B12 (µg) vs. placental weight (g) 0.005 0.921 − 7.34 8.12
 Trimester 2 dietary intakes
  Trimester 2 dietary iron (mg) vs. placental weight (g) − 0.025 0.606 − 5.68 3.32
  Trimester 2 dietary folate (µg) vs. placental weight (g) − 0.003 0.953 − 0.17 0.16
  Trimester 2 dietary B12 (µg) vs. placental weight (g) 0.044 0.366 − 4.06 10.99
 Trimester 3 dietary intakes
  Trimester 3 dietary iron (mg) vs. placental weight (g) 0.004 0.943 − 4.13 4.45
  Trimester 3 dietary folate (µg) vs. placental weight (g) 0.028 0.574 − 0.10 0.19
  Trimester 3 dietary B12 (µg) vs. placental weight (g) 0.008 0.873 − 5.05 5.94
 Full blood count results
  Early HgB (g/dL) vs. placental weight (g) − 0.050 0.249 − 25.62 6.66
  Late HgB (g/dL) vs. placental weight (g) − 0.103 0.021 − 35.05 − 2.86
Linear regression models for birthweight
 Trimester 1 dietary intakes
  Trimester 1 dietary iron (mg) vs. birthweight (g) 0.024 0.598 − 8.38 14.53
  Trimester 1 dietary folate (µg) vs. birthweight (g) 0.014 0.755 − 0.33 0.46
  Trimester 1 dietary B12 (µg) vs. birthweight (g) 0.003 0.941 − 19.06 20.56
 Trimester 2 Dietary Intakes
  Trimester 2 dietary iron (mg) vs. birthweight (g) 0.044 0.321 − 5.78 17.59
  Trimester 2 dietary folate (µg) vs. birthweight (g) − 0.005 0.908 − 0.46 0.41
  Trimester 2 dietary B12 (µg) vs. birthweight (g) 0.076 0.086 − 2.47 36.99
 Trimester 3 dietary intakes
  Trimester 3 dietary iron (mg) vs. birthweight (g) 0.041 0.369 − 6.22 16.70
  Trimester 3 dietary folate (µg) vs. birthweight (g) 0.012 0.783 − 0.33 0.44
  Trimester 3 dietary B12 (µg) vs. birthweight (g) 0.046 0.301 − 6.66 21.47
 Full blood count results
  Early HgB (g/dL) vs. birthweight (g) − 0.023 0.560 − 54.17 29.37
  Late HgB (g/dL) vs. birthweight (g) − 0.107 0.010 − 95.43 − 13.10

Model adjusted for randomised control trial group, maternal body mass index at booking, maternal age at delivery, dietary supplement use in pregnancy and socioeconomic status (maternal education level)

Early HgB hemoglobin at 13 weeks’ gestation, Late HgB hemoglobin at 28 weeks’ gestation