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. 2023 Sep 28;271(1):472–485. doi: 10.1007/s00415-023-11980-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The map of POMS cases from the PPMS Study and ROMS cases, controls from the AusImmune Study¹. 1. AusImmune Study participants were recruited from four study regions: Brisbane City (latitude 27° South), Newcastle City and surrounds (33° South), Geelong City and the Western Districts of Victoria (37° South), and the island state of Tasmania (43° South)