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. 2024 Jan 5;7:32. doi: 10.1038/s42003-023-05669-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Heatmaps show the interaction counts between 33 immune cell subsets in NP (left panel) and PE (right panel). b Dot plot shows the interactions between cytotoxic cell subsets and other cell subsets through the expression of stimulatory and inhibitory pairs in NP and PE. c Dot plot shows the interactions between B cell subsets with other cell subsets through the expression of stimulatory pairs in NP and PE. d Dot plot shows the interactions among immune cell subsets through the expression of chemokine-receptor pairs and other functional pairs in NP and PE. e Dot plot shows the interactions between T cell subsets and APCs through the expressions of co-stimulatory and co-inhibitory pairs in NP and PE. f Dot plot shows the interactions between cytotoxic cell subsets and APCs through the expression of inhibitory pairs in NP and PE. g Dot plot shows the interactions between Switched Memory B 1 and other cell subsets through the expression of stimulatory pairs in NP and PE. See also Supplementary Data 3.