Figure 3.

Estimation of unregulated leak respiration of isolated kidney cortex mitochondria of C57 black 6 mice receiving vehicle, low-dose (400 ng/kg/min) angiotensin II (Ang II), or high-dose (1,000 ng/kg/min) Ang II for 4 weeks. Panels show absolute oxygen consumption (QO₂) after the addition of oligomycin, GDP, and CAT to inhibit regulated pathways of QO₂. Data presented as means ± SEM. Statistical comparisons between all groups were made using a one-way ANOVA followed by Tukey’s post hoc test. * denotes P < 0.05 compared to vehicle-treated group, and # denotes P < 0.05 compared to low-dose treatment.