Table 3. Associations Between History of Infertility and Estimated Values for the 4 Components of Life’s Essential 8 Biomedical Domain in Project Viva at Midlife (N = 468).
| Outcome at midlife | Mean (SD) | β (95% CI)a | |
|---|---|---|---|
| Model 1 | Model 2 | ||
| Body mass indexb | 28.0 (6.5) | −0.10 (−1.36 to 1.17) | 0.18 (−0.95 to 1.32) |
| Blood pressure, mm Hg | |||
| Systolic | 116.3 (14.4) | 0.34 (−2.50 to 3.18) | 0.62 (−2.15 to 3.39) |
| Diastolic | 73.5 (10.9) | −0.63 (−2.77 to 1.52) | −0.45 (−2.54 to 1.65) |
| Blood lipids, mg/dL | |||
| HDL cholesterol | 68.8 (22.7) | −1.19 (−5.64 to 3.26) | −1.39 (−5.77 to 3.00) |
| Non-HDL cholesterol | 140.0 (41.9) | 7.90 (−0.18 to 15.99) | 7.66 (−0.52 to 15.83) |
| Glycemia | |||
| Fasting glucose, mg/dL | 91.8 (18.1) | 6.62 (2.96 to 10.29) | 6.31 (2.63 to 9.98) |
| Hemoglobin A1c, % | 5.3 (0.6) | 0.23 (0.11 to 0.35) | 0.23 (0.11 to 0.34) |
Abbreviation: HDL, high-density lipoprotein.
SI conversion factors: To convert cholesterol to millimoles per liter, multiply by 0.0259; glucose to millimoles per liter, multiply by 0.0555; hemoglobin A1c to proportion of total hemoglobin, multiply by 0.01.
Values are β coefficients (95% CI) for multivariable linear regression adjusted for age at outcome (model 1) and age at outcome, race and ethnicity (Hispanic, non-Hispanic Black, non-Hispanic White, or other, which includes American Indian or Alaska Native, non-Hispanic Asian or Pacific Islander, and participants who endorsed more than 1 race), age at menarche, perceived weight at age 10 years, and enrollment education (college graduate, yes/no) and household income (>$70 000, yes/no) (model 2).
Body mass index is calculated as weight in kilograms divided by height in meters squared.