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. 2024 Jan 5;7(1):e2350630. doi: 10.1001/jamanetworkopen.2023.50630

Table. Reported Xylazine-Related Overdose Deaths, 2019-2022.

State No. (rate per 100 000 residents)a Additional information Source
2019 2020 2021 2022
AK NR NR NR NR NA NA
AL NR NR 14 (0.3) 55 (1.1) NA Gulf Coast HIDTA,30 2023
AR NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
AZ NR NR NR NR Jan 2021-June 2022: between 10-99 IMF deaths xylazine-positive Kariisa et al,7 2023
CA NR NR NR NR 2021: 0.5% of Sampled deaths xylazine-positive, 0.3% xylazine-involved CA Department of Public Health,23 2023
CO NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
CT 71 (2.0) 141 (4.0) 298 (8.3) 354 (9.8) Xylazine-involved deaths CT Department of Public Health,24,25 2023
DC NR 3 (0.4) 6 (0.9) 11 (1.6) Xylazine-involved deaths DC Office of the Chief Medical Examiner,26 2023
DE NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
FL NR NR NR (1.1)b,c Xylazine-involved; based on first half of year FL Department of Law Enforcement,28 2023
GA NR 15 (0.1) 116 (1.1) 222 (2.1) Xylazine-involved GA Department of Public Health,29 2023
HI NR NR NR NR NA NA
IA NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
ID NR NR NR NR NA NA
IL 53 (0.4) 64 (0.5) 188 (1.5) NA (2.3)b,c Xylazine-involved; 2022 rate based on first half of year Feinberg School of Medicine,27 2023
IN NR NR NR NR Jan 2021-June 2022: 82 IMF deaths xylazine-involved Kariisa et al,7 2023
KS NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
KY NR NR NR NR In 2022: 1-5 xylazine-positive deaths KY Office of Drug Control Policy,31 2023
LA 3 (0.1) 21 (0.5) 39 (0.8) 25 (0.5)d Xylazine-involved LA State Board of Medical Examiners,32 2023
MA NR NR NR NR In 2022: of opioid deaths with toxicology, 5% xylazine-positive MA Department of Public Health,33 2023
MD 103 (1.7) 344 (5.7) 495 (8.0) NR Xylazine-positive Friedman et al,8 2022
ME NR NR 53 (3.9) 46 (3.4) Xylazine-involved Sorg et al,45 2022; Sorg et al,46 2023
MI NR NR 60 (0.6) 92 (0.9) Xylazine-positive MI Department of Health and Human Services,34 2023
MN 4 (0.1) 8 (0.1) 24 (0.4) 34 (0.6)d Xylazine-involved MN Department of Health,35 2023
MO 4 (0.1) 2 (0.0) 39 (0.6) 109 (1.8)d Xylazine-involved Nickelson,40 2023
MS NR NR NR NR Jan 2020-Jun 2022: 19 Xylazine-involved deaths MS State Department of Health,36 2023
MT NR NR NR NR NA NA
NC NR NR NR NR NA NA
ND NR NR NR NR Jan 2019-July 2023: 9 Xylazine-positive deaths ND Department of Health and Human Services,41 2023
NE NR NR NR NR 2021-2022: 4 Xylazine-involved deaths NE Department of Health and Human Services,37 2023
NH NR NR NR 3 (0.2)d Xylazine-involved NH Office of Chief Medical Examiner,38 2023
NJ 13 (0.1) 34 (0.4) 226 (2.4)d 210 (2.3)d NA Bureau of Justice Assistance,22 2023
NM NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
NV NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
NY NR NR NR NR 2021: 429 xylazine-involved opioid deaths in NYC; 135 in New York State outside NYC NY State Department of Health,39 2023
OH 15 (0.1) 45 (0.4) 75 (0.6) 119 (1.0)d Xylazine-involved OH Department of Health,42 2023
OK NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
OR NR 2 (0.0) 9 (0.2) 9 (0.2)d Xylazine-positive OR Health Authority,43 2023
PA 259 (2.0) 377 (2.9) 576 (4.4) 760 (5.9) Xylazine-involved PA Department of Health,44 2023
RI NR NR NR NR Jan 2021-June 2022: between 10-99 IMF deaths xylazine-positive Kariisa et al,7 2023
SC NR NR NR NR Jan 2021-June 2022: 178 IMF deaths involving xylazine Kariisa et al,7 2023
SD NR NR NR NR NA NA
TN NR 56 (0.8) 94 (1.3) NR Xylazine-involved TN Department of Health,47 2022
TX NR NR 11 (0.0) 19 (0.1) Xylazine-involved TX Department of State Health Services,48 2023
UT NR NR NR NR NA NA
VA NR NR NR NR Jan 2021-June 2022: between 10-99 IMF deaths xylazine-positive Kariisa et al,7 2023
VT 6 (1.0) 5 (0.8) 29 (4.5) 68 (10.5) Xylazine-involved VT Department of Health,49 2023
WA NR NR NR NR Jan 2021-June 2022: between 1-9 IMF deaths xylazine-positive Kariisa et al,7 2023
WI NR NR NR NR 2019-2020: 6 xylazine-positive deaths reported in Milwaukee Friedman et al,8 2022
WV 10 (0.6) 67 (3.8) (4.5)b,c NR Xylazine-positive Sibbesen et al,5 2023
WY NR NR NR NR NA NA

Abbreviations: IMF, illicitly manufactured fentanyl; NA, not available; NR, not reported.

a

Death counts were most recently accessed from each source October 27 to 30, 2023. Rates are per 100 000 population and calculated using population estimates from the National Center for Health Statistics.

b

Totals provided for a half-year period, and not included.

c

Data provided for half of year only.

d

Data source indicates this figure is based on provisional data.