Table 1.
The global burden of breast cancer attributable to tobacco in 1990 and 2019 and the temporal trends during 1990–2019
| Characteristics | 1990 | 2019 | EAPC of ASMR No. (95% CI) | EAPC of ASDR No. (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Death number No. × 102 (95% UI) | ASMR per 100000 No. (95% UI) |
DALY No. × 103 (95% UI) |
ASDR per 100000 No. (95% UI) |
Death number No. × 102 (95% UI) | ASMR per 100000 No. (95% UI) |
DALY No. × 103 (95% UI) |
ASDR per 100000 No. (95% UI) |
|||
| Global | 258.57 (172.83–343.33) | 1.21 (0.82–1.61) | 805.99 (515.63–1087.75) | 36.93 (23.87–49.78) | 354.39 (221.79–481.19) | 0.82 (0.51–1.11) | 1060.59 (622.55–1462.58) | 24.60 (14.37–34.04) | -1.55 (-1.62–1.49) | -1.59 (-1.68–1.53) |
| Socio-demographic index | ||||||||||
| Low SDI | 6.16 (2.85–9.52) | 0.49 (0.23–0.75) | 20.85 (9.00–32.79) | 14.66 (6.55–22.80) | 16.69 (8.07–25.56) | 0.59 (0.30–0.89) | 55.09 (24.51–86.73) | 17.24 (8.17–26.68) | 0.62 (0.55–0.68) | 0.49 (0.42–0.57) |
| Low-middle SDI | 22.26 (10.33–33.99) | 0.70 (0.34–1.05) | 75.24 (32.30–116.39) | 21.27 (9.56–32.65) | 49.60 (21.97–76.16) | 0.67 (0.31–1.03) | 159.87 (65.09–249.53) | 20.45 (8.58–31.80) | -0.3 (-0.4–0.2) | -0.34 (-0.46–0.22) |
| Middle SDI | 37.55 (16.92–57.03) | 0.67 (0.31–1.02) | 127.68 (53.73–199.10) | 20.95 (9.10–32.30) | 81.26 (36.86–124.57) | 0.61 (0.28–0.93) | 261.27 (108.17–406.04) | 18.88 (7.87–29.26) | -0.46 (-0.56–0.37) | -0.49 (-0.58–0.40) |
| High-middle SDI | 70.97 (45.11–95.20) | 1.20 (0.76–1.61) | 226.20 (139.47–306.12) | 38.56 (23.75–52.31) | 98.71 (63.72–134.37) | 0.91 (0.58–1.24) | 291.51 (180.74–398.52) | 27.92 (17.04–38.29) | -1.24 (-1.36–1.14) | -1.4 (-1.53–1.30) |
| High SDI | 121.46 (88.12–152.26) | 2.20 (1.61–2.75) | 355.52 (257.28–446.58) | 69.17 (50.15–87.03) | 107.86 (77.52–137.29) | 1.16 (0.83–1.46) | 292.01 (210.18–368.17) | 35.70 (25.54–45.15) | -2.4 (-2.51–2.35) | -2.46 (-2.56–2.43) |
| GBD region | ||||||||||
| High-income Asia Pacific | 5.97 (3.78–8.04) | 0.54 (0.34–0.73) | 20.38 (12.27–27.94) | 18.70 (11.18–25.76) | 8.82 (5.75–11.92) | 0.47 (0.30–0.63) | 25.99 (16.59–35.35) | 16.39 (10.04–22.46) | -0.27 (-0.42–0.13) | -0.27 (-0.44–0.10) |
| High-income North America | 48.65 (34.08–62.26) | 2.69 (1.92–3.41) | 145.93 (105.35–184.63) | 86.93 (63.48–108.87) | 42.21 (29.11–55.27) | 1.31 (0.93–1.70) | 115.43 (83.14–148.34) | 39.67 (28.91–50.59) | -2.67 (-2.80–2.61) | -2.92 (-3.06–2.87) |
| Central Asia | 2.21 (0.95–3.39) | 0.80 (0.34–1.22) | 7.45 (3.11–11.51) | 26.84 (11.21–41.65) | 2.91 (1.22–4.52) | 0.65 (0.27–1.00) | 9.73 (3.98–15.14) | 20.38 (8.41–31.66) | -0.65 (-0.73–0.57) | -0.98 (-1.07–0.91) |
| East Asia | 22.45 (7.99–36.68) | 0.48 (0.18–0.77) | 76.64 (25.23–128.11) | 15.31 (5.13–25.44) | 48.80 (21.21–78.60) | 0.45 (0.20–0.73) | 150.58 (58.84–244.45) | 13.95 (5.37–22.62) | -0.38 (-0.50–0.27) | -0.56 (-0.68–0.44) |
| South Asia | 17.60 (7.21–28.54) | 0.60 (0.26–0.97) | 59.99 (22.45–97.40) | 17.98 (7.18–29.04) | 47.44 (19.60–76.30) | 0.64 (0.27–1.02) | 153.47 (58.39–252.32) | 19.40 (7.58–31.68) | -0.03 (-0.16–0.11) | 0.03 (-0.12–0.18) |
| Southeast Asia | 16.40 (6.91–25.37) | 1.10 (0.49–1.68) | 57.45 (21.89–92.89) | 34.88 (14.21–55.13) | 34.00 (13.90–54.54) | 0.98 (0.41–1.56) | 114.96 (42.79–189.75) | 31.49 (11.89–51.81) | -0.5 (-0.61–0.40) | -0.45 (-0.54–0.36) |
| Central Europe | 16.11 (11.49–20.56) | 2.00 (1.43–2.58) | 49.69 (35.34–64.01) | 63.78 (45.15–82.91) | 18.97 (13.25–25.42) | 1.72 (1.21–2.31) | 51.20 (36.22–69.11) | 51.51 (35.96–69.72) | -0.67 (-0.74–0.60) | -0.91 (-0.99–0.83) |
| Eastern Europe | 15.62 (8.21–22.42) | 0.97 (0.50–1.39) | 51.84 (26.71–74.45) | 34.00 (17.69–48.93) | 18.48 (10.85–26.60) | 0.98 (0.57–1.41) | 57.40 (33.23–82.80) | 32.92 (18.92–47.72) | -0.57 (-0.82–0.33) | -0.76 (-1.02–0.50) |
| Western Europe | 76.72 (56.24–95.61) | 2.62 (1.92–3.29) | 220.56 (160.96–277.57) | 83.08 (60.56–105.03) | 66.54 (48.63–84.20) | 1.54 (1.12–1.93) | 177.65 (129.05–223.65) | 47.83 (34.36–60.79) | -2.12 (-2.26–2.03) | -2.17 (-2.29–2.10) |
| Andean Latin America | 0.40 (0.20–0.60) | 0.36 (0.18–0.53) | 1.31 (0.61–1.99) | 10.96 (5.27–16.45) | 0.87 (0.46–1.33) | 0.29 (0.16–0.44) | 2.62 (1.28–4.12) | 8.62 (4.29–13.47) | -1.01 (-1.16–0.88) | -1.16 (-1.31–1.02) |
| Central Latin America | 3.41 (2.08–4.73) | 0.75 (0.47–1.03) | 10.75 (6.17–15.14) | 21.80 (12.93–30.50) | 6.41 (3.67–9.43) | 0.50 (0.29–0.73) | 19.25 (10.21–29.07) | 14.58 (7.80–22.04) | -1.52 (-1.62–1.44) | -1.51 (-1.62–1.43) |
| Southern Latin America | 7.40 (5.35–9.56) | 2.93 (2.10–3.79) | 21.05 (14.84–27.57) | 84.24 (59.13–110.49) | 9.39 (6.64–12.16) | 2.07 (1.46–2.68) | 24.47 (17.12–31.86) | 57.03 (39.17–74.81) | -1.24 (-1.33–1.17) | -1.37 (-1.45–1.31) |
| Tropical Latin America | 9.07 (6.60–11.62) | 1.80 (1.31–2.30) | 28.49 (20.07–36.74) | 52.60 (37.46–67.64) | 13.44 (9.45–17.56) | 1.00 (0.70–1.31) | 38.98 (26.72–51.81) | 28.88 (19.80–38.37) | -2.09 (-2.42–1.81) | -2.11 (-2.46–1.80) |
| Australasia | 2.98 (2.22–3.73) | 2.50 (1.85–3.13) | 9.09 (6.68–11.53) | 79.87 (58.59–101.26) | 2.71 (1.96–3.43) | 1.14 (0.82–1.45) | 7.96 (5.66–10.20) | 36.74 (25.93–47.39) | -2.88 (-3.10–2.74) | -2.83 (-3.03–2.73) |
| Caribbean | 1.47 (1.01–1.95) | 1.09 (0.75–1.45) | 4.45 (2.92–5.97) | 32.25 (21.37–43.17) | 2.63 (1.78–3.56) | 0.96 (0.65–1.29) | 7.34 (4.82–10.12) | 27.14 (17.75–37.43) | -0.26 (-0.36–0.16) | -0.43 (-0.53–0.33) |
| North Africa and Middle East | 5.75 (2.69–8.76) | 0.61 (0.29–0.93) | 20.28 (9.17–31.19) | 19.83 (9.09–30.34) | 16.17 (7.40–24.87) | 0.69 (0.32–1.04) | 56.14 (24.72–88.41) | 21.76 (9.83–33.89) | 0.46 (0.39–0.52) | 0.33 (0.27–0.39) |
| Oceania | 0.45 (0.22–0.66) | 2.64 (1.37–3.89) | 1.58 (0.75–2.39) | 84.59 (41.62–126.51) | 1.25 (0.62–1.99) | 3.03 (1.57–4.71) | 4.50 (2.09–7.31) | 97.48 (47.91–155.93) | 0.59 (0.53–0.64) | 0.61 (0.55–0.67) |
| Central Sub-Saharan Africa | 0.43 (0.19–0.70) | 0.33 (0.15–0.52) | 1.48 (0.60–2.46) | 9.79 (4.12–16.12) | 1.23 (0.50–2.12) | 0.38 (0.16–0.65) | 4.24 (1.62–7.37) | 11.49 (4.64–19.88) | 0.43 (0.30–0.55) | 0.44 (0.32–0.55) |
| Eastern Sub-Saharan Africa | 1.59 (0.70–2.47) | 0.40 (0.19–0.61) | 5.28 (2.14–8.43) | 11.44 (4.98–17.91) | 4.19 (2.02–6.47) | 0.47 (0.25–0.71) | 13.43 (5.84–21.56) | 12.84 (5.97–19.91) | 0.55 (0.49–0.60) | 0.34 (0.26–0.42) |
| Southern Sub-Saharan Africa | 2.16 (1.28–3.09) | 1.37 (0.82–1.98) | 6.64 (3.78–9.50) | 39.04 (22.67–55.92) | 3.47 (1.93–4.93) | 1.07 (0.60–1.51) | 9.91 (5.19–14.45) | 28.49 (15.10–41.35) | -0.67 (-0.89–0.46) | -0.8 (-1.00–0.61) |
| Western Sub-Saharan Africa | 1.71 (0.68–2.83) | 0.38 (0.15–0.61) | 5.65 (2.09–9.48) | 11.38 (4.34–18.90) | 4.48 (1.74–7.37) | 0.41 (0.17–0.65) | 15.36 (5.56–25.48) | 12.07 (4.64–19.95) | 0.24 (0.18–0.30) | 0.2 (0.12–0.27) |
ASMR Age-standardized mortality rate, UI Uncertainty interval, DALYs Disability-adjusted life years, ASDR Age-standardized DALY rate, EAPC Estimated annual percentage change, CI Confidence interval, SDI Socio-demographic Index