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. 2023 Jun 2;55(1):96–102. doi: 10.1093/labmed/lmad041

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© The Author(s) 2023. Published by Oxford University Press on behalf of American Society for Clinical Pathology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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FIGURE 2. — Comparison of metagenomic next-generation sequencing (mNGS), Xpert MTB/RIF, Mycobacterium tuberculosis (MTB) culture, and acid-fast bacillus (AFB) staining for the detection of MTB complex (MTBC). A, Heatmap depicting the identification of MTBC by the 4 methods in bronchoalveolar lavage fluid samples. Each column represents a patient. B, The number of positive and negative findings by each of the 4 methods in all 186 enrolled patients. C, For mNGS, Xpert MTB/RIF, and MTB culture, the number and percentage of patients with positive or negative findings by 1, 2, or 3 methods in 142 patients are shown in the pie chart. D, The number of positive and negative findings by each of the 4 methods in 38 pulmonary tuberculosis (PTB) patients. *P < .05; **P < .01; ***P < .001.

FIGURE 2. — Comparison of metagenomic next-generation sequencing (mNGS), Xpert MTB/RIF, Mycobacterium tuberculosis (MTB) culture, and acid-fast bacillus (AFB) staining for the detection of MTB complex (MTBC). A, Heatmap depicting the identification of MTBC by the 4 methods in bronchoalveolar lavage fluid samples. Each column represents a patient. B, The number of positive and negative findings by each of the 4 methods in all 186 enrolled patients. C, For mNGS, Xpert MTB/RIF, and MTB culture, the number and percentage of patients with positive or negative findings by 1, 2, or 3 methods in 142 patients are shown in the pie chart. D, The number of positive and negative findings by each of the 4 methods in 38 pulmonary tuberculosis (PTB) patients. *P < .05; **P < .01; ***P < .001.