Table 7.
Thermal, pH, salts, and protease stability of Ple-AB against S. aureus ATCC 43300.
Treatment | MIC (μg/mL) | |
---|---|---|
Ple-AB | ||
Control | 16 | |
Temperature | ||
20°C | 16 | |
40°C | 16 | |
60°C | 16 | |
80°C | 16 | |
100°C | 32 | |
pH | ||
2 | 16 | |
4 | 16 | |
6 | 16 | |
8 | 16 | |
10 | 32 | |
Salts | ||
Na+ (150 mM) | 16 | |
K+ (4.5 mM) | 16 | |
NH4+ (6 μM) | 16 | |
Zn2+ (8 μM) | 16 | |
Mg2+ (1 mM) | 16 | |
Ca2+ (2.5 mM) | 16 | |
Fe3+ (4 μM) | 16 | |
Simulated Gastric Fluid (1-2 h) | 16 | |
Artificial Intestinal Fluid (1 h) | 32 | |
Serum (25%) (1–8 h) | 16 | |
Serum (50%) (1–8 h) | 16 |