Comparison 18. Quality of life at two years: etanercept + disease‐modifying anti‐rheumatic drug (DMARD) vs. DMARD.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Percentage improvement in HAQ (from baseline)	1	459	Mean Difference (IV, Fixed, 95% CI)	20.0 [17.45, 22.55]
1.1 Etanercept 25 mg SC twice weekly	1	459	Mean Difference (IV, Fixed, 95% CI)	20.0 [17.45, 22.55]
2 HAQ score after treatment	2	610	Mean Difference (IV, Random, 95% CI)	‐0.49 [‐0.69, ‐0.30]
2.1 Etanercept 25 mg SC twice weekly	2	610	Mean Difference (IV, Random, 95% CI)	‐0.49 [‐0.69, ‐0.30]