Fig. 2.

CSF p-tau205 and p-tau202 levels across CSF AT groups. In the Paris cohort, a CSF p-tau205 increased progressively across the groups stratified by Aβ (A) and tau (T) positivity, b whereas CSF p-tau202 was only increased in A+T+ group. In the TRIAD cohort, c CSF p-tau205 increased in a stepwise manner across AT groups d while high levels of CSF p-tau202 were only present in A+T+. Data information: Boxplots show the median, IQR and all participants. Participants colour-coded based on the presence (red) or absence (blue) of CSF amyloidosis measured with Lumipulse CSF Aβ42/40. P-values were determined using one-way ANOVA adjusted by age and sex, followed by Bonferroni-corrected post hoc comparison (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)